TherapeuticTarget相关论文
Objective:To explore the mechanisms of Dangua Recipe (DGR) in improving glycolipid metabolism based on transcriptomics.M......
Application of immune checkpoint targets in the anti-tumor novel drugs and traditional Chinese medic
Immune checkpoints are the crucial regulators of immune system and play essential roles in maintaining self-tolerance,pr......
Objective Lung cancer is a type of malignant tumor with high morbidity and mortality.Due to its complicated etiology and......
Osteosarcoma is the most prevalent primary cancer in the bones.Osteosarcoma cells are highly metastatic and frequently d......
Long noncoding RNA LINC01296 promotes cancer-cell proliferation and metastasis in urothelial carcino
Objective LncRNAs have been demonstrated to have important functions in the development and progression of bladder cance......
Identification and Validation of Differentially Expressed Proteins in Epithelial Ovarian Cancers Usi
Ovarian cancer is the most lethal gynecological malignant tumor that has greatly compromised patients life span and qual......
Autophagy has been recently suspected to plays an important role in the regulation of cancer development and the respons......
Background: Urothelial carcinoma of the bladder is a major cause of morbidity and mortality worldwide.Although localized......
Chaperone-mediated autophagy and neurodegeneration:connections,mechanisms,and therapeutic implicatio
Lysosomes degrade dysfunctional intracellular components via th ree pathways:macroautophagy,microautophagy,and chaperone......
Targeting galectin-1 reduce the severity of DNA damage and inflammation caused by Mycoplasma pneumon
Objective Mycoplasma pneumoniae is one of the major etiological agents causing respiratory infection worldwide in all ag......
50% of mortalities attributable to cardiac causes are accounted for by cardiac arrhythmias occurring either independentl......
APE1 overexpression promotes the progression of ovarian cancer and serves as a potential therapeutic
BACKGROUND: Apurinic/apyrimidinic endonuclease 1 (APE1) has been recognized as a promising anticancer target in several ......
Basal autophagy is tightly regulated by transcriptional and epigenetic factors to maintain cellular homeostasis.Dysregul......
Vitiligo is an acquired depigmenting skin disease that affects 0.5%to 2% of the world population.1 The current available......
Critically dysregulated signaling pathways and clinical utility of the pathway biomarkers in lymphoi
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Fibronectin type Ⅲ domain-containing 5 in cardiovascular and metabolic diseases:a promising biomarke
Cardiovascular and metabolic diseases are the leading causes of death and disability worldwide and impose a tremendous s......
The expression of platelet-activating factor receptor modulates the cisplatin sensitivity of ovarian
Objective:Ovarian cancer has the highest mortality rate of the gynecological cancers.Although cisplatin (CDDP),is ef......
精神分裂症是一种严重的精神疾病,但确切的机制至今尚未研究透彻. 近来,研究者们发现D1、D2 受体的过度活化、多巴胺和环腺苷酸调......
